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| | 2010 |
Sugawara, M., Resende, J.M., Mendonca de Moraes, C., Chich, J.F., Marquette, A., Metz-Boutigue, M.H., and Bechinger B., Membrane structure and interactions of human Catestatin by multidemansional solution and solid-state NMR spectroscopy FASEB Journal (in press 2010)
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Georgescu, J., & Bechinger, B. NMR
structures of the histidine-rich peptide LAH4 in micellar environments:
membrane insertion, pH-dependent mode of antimicrobial action and DNA
transfection (submitted) | | |
Marquette, A., Lorber, B., and Bechinger B., Reversible
association of liposomes by LAH4 - a peptide with potent antimicrobial
and nucleic acid transfection activities, Biophysical Journal (in press
2010) | | Langlet-Bertin, B., Leborgne, C., Scherman, D., Bechinger B., Mason; A.J., and Kichler, A. Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery (submitted) | | Salnikov, E., Aisenbrey, C., Vidovic, V. and Bechinger, B. Solid-state NMR spectroscopic approaches to measure topological equilibria and dynamics of membrane polypeptides invited contribution to ‘Membrane Protein Dynamics : Correlating Structure to Function’, Editors: A. Ramamoorthy and G. Veglia, Biochimica et Biophysica Acta - Membrane Reviews 1798, 258-265 (2010) |
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| | 2009 | Evgeniy Salnikov, Xing Li, Philippe Bertani, Joe D. J. O’Neil , Jan Raap and Burkhard Bechinger Analysis
of the amide 15N chemical shift tensor of the Calpha tetrasubstituted
constituent of membrane-active peptaibols,
the alpha-aminoisobutyric acid residue, compared to those of di-
and tri-substituted proteinogenic amino acid residues, Journal of Biomolecular NMR 45, 373-387 (2009) | | |
Resende,
J.M., Mendonca Moraes, C., de Oliveira Munhos, V.H., Aisenbrey, C.,
Verly, R.M., Bertani, P., Cesar, A., Piló-Veloso, D., and Bechinger, B.
Membrane structure and conformational changes of the antibiotic
heterodimeric peptide distinctin by solid-state NMR spectroscopy,
Proceedings of the National Academy of Sciences USA 106, 16639-16644
(2009) | | |
Falk
Bernsmann, Arnaud Ponche, Christian Ringwald, Jesus Raya, Burkhard
Bechinger, Jean-Claude Voegel, Pierre Schaaf, and Vincent Ball
Characterization and control of the surface-initiated
dopamine-melanin growth on silicon oxides Journal of Physical Chemistry
B (in press 2009) | | Aisenbrey, C., Prongidi-Fix, L., Chenal, A., Gillet, D. and Bechinger, B. Side chain resonances in static oriented proton-decoupled 15N solid-state NMR spectra of membrane proteins, Journal of the American Chemical Society 131, 6340-6341 (2009) | | Bechinger, B. Rationalizing the membrane interactions of cationic amphipathic antimicrobial peptides by their molecular shape Current Opinion in Colloid and Interface Science, Surfactants 14, 349-355 (2009) | | Alexandre
Chenal, Lydia Prongidi-Fix, Aurélie Perier, Christopher Aisenbrey,
Grégory Vernier, Stephan Lambotte, Michael Haertlein, Marie-Thérèse
Dauvergne, Giovanna Fragneto, Burkhard Bechinger, Daniel Gillet,
Vincent Forge, and Michel Ferrand; Deciphering membrane
insertion of the diphtheria toxin T domain by specular neutron
reflectometry and solid state NMR spectroscopy. Journal of Molecular Biology, cover page of 50 years of JMB issue 391 (5), 872-883 (2009) | | Salnikov, E., De Zotti, M., Formaggio, F., Li, X., Toniolo, C., O’Neil, J. D. J., Raap, J., Dzuba, S., and Bechinger, B. Alamethicin
topology in phospholipid membranes by oriented solid-state NMR and EPR
spectroscopies: A comparison Journal of Physical Chemistry B 113,
3034-3042 (2009) | | Evgeniy Salnikov, A. James Mason and Burkhard Bechinger Membrane disordering in the presence of antimicrobial peptides by 2H solid-state NMR spectroscopy Biochimie 91, 734-743 (2009) | | Mason,
A.J., Moussaoui, W., Abdelrhaman, T., Boukhari, A., Bertani, P.,
Marquette, A., Shooshtarizaheh, P., Moulay, G., Boehm, N., Guerold, B.,
Kichler, A., Metz-Boutigue, M.H., Candolfi, E., Prévost, G., and
Bechinger, B. Structural determinants of antimicrobial and
antiplasmodial activity and selectivity in histidine rich amphipathic
cationic peptides Journal of Biological Chemistry 284, 119-133 (2009) | | |
Vidovic, V., Prongidi-Fix, L., Bechinger, B., and Werten S. A versatile and highly efficient method for the production of antimicrobial peptides in Escherichia coli. Journal of Peptide Science 15, 278-284 (2009) | | Verly,
R.M., Mendonça de Moraes, C., Resende, J.M., Aisenbrey, C., Bemquerer,
M.P., Piló-Veloso, D., Valente, A.P., de Almeida, F.C.L., and
Bechinger, B. Structure and membrane interactions of the antibiotic
peptide dermadistinctin k by solution and oriented 15N and 31P
solid-state NMR spectroscopy Biophysical Journal 18, 2194-2203 (2009) | | Evgeniy
Salnikov, Herdis Friedrich, Xing Li , Philippe Bertani, Christian
Hertweck, Siegmund Reissmann, Joe D. J. O’Neil, Jan Raap and Burkhard
Bechinger Structure and alignment of the membrane-associated
peptaibols ampullosporin A and alamethicin by oriented 15N and 31P
solid-state NMR spectroscopy Biophysical Journal 96, 86-100 (2009) | | | |
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| | 2008 | |
Svetlana Nedelkina, Helen Ridlley, Isa Gokce, Thierry Magnin, Francois Vallette, Franc Pattus, Jeremy Lakey, Burkhard Bechinger High-yield
expression and purification of soluble form of anti-apoptotic proteins
Bcl-xL and Bcl-2 as a TolAIII- fusion proteins Protein Expression and Purification 29, 1633-1644 (2008) | | |
Bechinger, B. The Structure and Dynamics of Membranes: Polypeptide Interactions in a Polymorphic Environment invited review to the special issue Membrane structure and Dynamics, Cellular and Molecular Life Sciences 65, 3028-3039 (2008) | | |
Jarbas
M. Resende, Cléria Mendonça Moraes, Amary Cesar, Fabio C. L. Almeida,
Maura V. Prates, Nathália C. C. R. Mundim, Philippe Bertani, Ana Paula
Valente, Marcelo P. Bemquerer, Dorila Piló-Veloso, and Burkhard
Bechinger Structure, activity and membrane interaction studies of
Phylloseptin 1, 2, and 3 peptides by solution and combined 15N and 2H
solid-state NMR spectroscopy, Peptides 29, 1633-1644 (2008) | | Aisenbrey, C., Cusan, M., Lambotte, S., Jasperse, P., Georgescu, J., Harzer, U., and Bechinger, B. Specific
isotope labeling of colicin E1 and B channel domains for membrane
topological analysis by oriented solid-state NMR spectroscopy Chem.Bio.Chem 9, 944-51 (2008) | | Marquette, A., Mason J. and Bechinger, B. Aggregation and membrane permeabilising properties of designed histidine-containing cationic linear peptide antibiotics, Jounal of Peptide Sciences 14, 488-495 (2008) | | Aisenbrey, C., Bechinger, B. and Gröbner, G. Effect on helix alignments of molecular crowding of peptides on the membrane surface Journal of Molecular Biology 375, 376-385 (2008) | |
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| | 2007 | Mason, A. J., Bertani, P., Moulay, G., Marquette, A., Perrone, B., Drake, A., Kichler, A., and Bechinger, B. The membrane interaction of chrysophsin, a histidine rich antimicrobial peptide from red sea bream Biochemistry 46, 15175-15187 (2007) | |
| Egger, C., Raman, V., Schädler, V, Raya, J., Hirschinger, J., and Bechinger, B., 1H-13C CP MAS and T2 Relaxation Solid-State NMR Measurements of Melamine-Based Polycondensed Chemical Gels Macromorecular Chemistry and Physics 208, 2204-2214 (2007) | |
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Prongidi-Fix, L., Bertani, P., and Bechinger, B. The membrane alignment of helical peptides from non-oriented 15N chemical shift solid-state NMR spectroscopy Journal of the American Chemical Society 129, 8430-8431 (2007) | | Mason, A.J., Marquette, A., and Bechinger, B. Zwitterionic lipids and sterols modulate antimicrobial peptide-membrane interactions Biophysical Journal 93, 4289-4299 (2007) | | Aisenbrey, C., Sudheendra U.S., Ridley, H., Bertani, P., Marquette, A., Nedelkina, S., Lakey, J., & Bechinger, B. Helix orientations in membrane-associated Bcl-xL determined by 15N solid-state NMR spectroscopy European Biophysics Journal 36, 451-460 (2007) | | Prongidi-Fix, L. Sugawara, M., Bertani, P., Raya, J., Leborgne, C., Kichler, A., and Bechinger, B., Self-promoted cell entry of peptidic transfection complexes Biochemistry 46, 11253-11262 (2007) | | Muhs,
A., Hickman, D.T., Kolonko, N., Pihlgren, M., van der Auwera, I., van
Leuven, F., Sugawara, M., Weingertner, M.C., Bechinger, B., Greferath,
R., Nagel-Steger, L., Riesner, D., Pfeifer, A. and Nicolau, C.,
Conformation-dependent antigen presentation within a liposomal vaccine
formulation reduces cerebral Aβ load and improves cerebral memory
capacities in Alzheimer’s Disease model Proceedings of the National Academy of Sciences USA 104, 9810-9815 (2007) | | Lalier, L., Cartron, P.-F., Juin, P., Nedelkina, S., Manon, S., Bechinger, B., Vallette, F. Bax activation and mitochondrial insertion during apoptosis , Review, Apoptosis, 12, 887-896 (2007) | | Mason, A.J., Leborgne, C., Moulay, G., Martinez, A., Danos, O., Bechinger, B., Kichler, A. Optimizing histidine-rich peptides for efficient DNA delivery in the presence of serum Journal of Controlled Release 118, 95-114 (2007) | | Aisenbrey, C., Bertani. P., Henklein, P., Bechinger, B. Structure,
Dynamics and Topology of membrane polypeptides by oriented 2H
solid-state NMR spectroscopy, contribution to the Festschrift in honour
to the 65th birthday of Professor Klaus Arnold. European Biophysical Journal 36, 451-460 (2007) | | Mason, J., Bechinger, B., & Kichler, A. Rational design of vector and antibiotic peptide using solid state NMR Mini-reviews in Medicinal Chemistry 7, 491-497 (2007) | | Kichler, A., Leborgne, C., Danos, O., Bechinger, B. Characterization of the gene transfer process mediated by histidine-rich peptides Journal of Molecular Medicine 85, 191-201 (2007) | | |
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| | 2006 |
Mason,
A.J., Gasnier, C., Kichler, A., Prévost, G., Metz-Boutigue, M.H., &
Bechinger, B. Enhanced membrane disruption and antibiotic action
against pathogenic bacteria by designed histidine-rich peptides at
acidic pH Antimicrobial Agents and Chemotherapy 50, 3305-3311 (2006) | |
Bechinger, B. and Lohner, K. Detergent-like action of linear cationic membrane-active antibiotic peptides Biochim. Biophys. Acta, 1758, 1529-1539 (2006) | | Aisenbrey, C., Kinder, R., Goormaghtigh, E., Ruysschaert, J.M., & Bechinger, B. Interactions
involved in the realignment of membrane-associated helices: an
investigation using oriented solid-state NMR and ATR-FTIR
spectroscopies Journal of Biological Chemistry 281, 7708-7716 (2006) | | Aisenbrey, C., Sizun, C., Koch, J., Hergert, M., Abele, R., Bechinger, B.*, and Tampé, R.*, Structure and dynamics of membrane-associated ICP47, a viral inhibitor of the MHC I antigen-processing machinery. J Biol Chem. 281, 30365-72. (2006) | | Aisenbrey, C., Goormaghtigh, E. , Ruysshaert, J.M., & Bechinger, B.
Translocation of amino acyl residues from the membrane interface to the
hydrophobic core: Thermodynamic model and experimental analysis using
ATR-FTIR spectroscopy Molecular Membrane Biology 23, 363-374 (2006) | | Mason, J.A., Husnal Chotimah, I.N., Bertani, P., and Bechinger, B. Aspectroscopic study of the membrane interaction of the antimicrobial peptide pleurocidin Molecular Membrane Biology 23, 185-194 (2006) | | Aisenbrey, C., Harzer, U., Bär, G., Bauer-Manz, G., Husnal Chotimah, I.N., Bertani, P., Kuhn, A., and Bechinger, B. Structure and membrane alignment of the Pf3 coat protein by 15N solid-state NMR spectroscopy FEBS Journal 273, 817-28 (2006) | |
Kichler, A., Mason, J., and Bechinger, B., Cationic amphipathic histidine-rich peptides for gene delivery Biochimica Biophysica Acta 1758, 301-307 (2006) | | Mason, J.A., Marinez, A. Glaubitz, C., Danos, O., Kichler, A., and Bechinger, B. The antibiotic and DNA transfecting peptide LAH4 selectively associates with, and disorders, anionic lipids in mixed membranes FASEB J. 20, 320-2 (2006) | |
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| | 2005 | |
Sudheendra U.S. & Bechinger, B. Topological equilibria of ion-channel peptides in oriented lipid bilayers revealed by 15N solid-state NMR spectroscopy Biochemistry, 44, 12120-12127 (2005) | | |
Bechinger, B., Detergent-like properties of magainin antibiotic peptides: A 31P solid-state NMR spectroscopy study Biochimica Biophysica Acta 1712, 101-108 (2005) | |
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| | Proceedings and Meeting Abstracts | |
Aisenbrey, C., Resende, J., Piló-Veloso, D., Bechinger, B: "Solid-state NMR investigations of membrane-associated peptides and proteins" Abstract for the Biophysical Society Meeting, San Francisco, USA, 18-24. February 2010 | | |
Perrone, B., Miles, A.J., Bechinger, B., Hoffman, S.V., Wallace, B.A. "Oriented Synchrotron Radiation Circular Dichroism and Linear Dichroism Spectrospscopy of Peptides in Model Membranes" Abstract
for the Biophysical Society Meeting, Boston, 28.2.-4.3.2009
http://www.abstractsonline.com/plan/SSResults.aspx
1724-Pos | | Salnikov, E., Friedrich, H., Li, X. , Bertani, P., Hertweck, C., Reissmann, S., O’Neil, J. D. J., Raap, J., and Bechinger, B.. "Structure and alignment of membrane-associated peptaibols by oriented 15N and 31P solid-state NMR spectroscopy" Abstract for the Biophysical Society Meeting, Boston, 28.2.-4.3.2009 http://www.abstractsonline.com/plan/SSResults.aspx 2101-Pos | | Bechinger, B. "Biophysical
investigations of membrane-associated polypeptides by solid-state NMR:
Applications to proteins and peptides involved in apoptosis, channel
formation, antimicrobial action and transfection of nucleic acids" Abstracts of Papers of the Amercian Chemical Society ACS Spring Meeting, New Orleans LA (April 6, 2008) | | Anna Itkin, Burkhard Bechinger, Jean-Marie Ruysschaert, Vincent Raussens Effects
of Ca+2 ions and lipids on aggregation and conformational changes of
synthetic amyloid beta-peptides associated with Alzheimer’s disease.
Biophys. J. (2008) | | Philippe
Bertani, Arnaud Marquette, A. James Mason, Sveltana Nedelkina, Marc
Prudhon, Evgeniy Salnikov, Verica Vidovic, Christopher Aisenbrey,
Robert, Tampé, Andreas Kuhn, Jeremy, H. Lakey, Burkhard Bechinger,
Structural Investigations of proteins and peptides by solid-state NMR
spectroscopy. Proceedings of the XVIII Mendeleev Congress on General and Applied Chemistry, Volume 5, Moscow (2007) | | Evgeniy S. Salnikov, Burkhard Bechinger, Jan Raap, Sergey A. Dzuba "Membrane
Composition Influences Topology of Membrane-Modifying Peptaibol
Alamethicin: Pulsed EPR and Solid State NMR Study"
Sendai-Berlin-Novosibirsk 2006, 28-31 August 2006, Novosibirsk, Russia, p.33 | | Prongidi-Fix, L., Aisenbrey, C., Mason, J., Kichler, A., Bechinger, B. "New family of peptidic vectors with potent transfection and antibiotic activities" Abstracts of Papers of the Amercian Chemical Society 231: 178PHYS ACS Spring Meeting, Atlanta, GA (March 26, 2006) | | Mason, J., Husnal Chotimah, I.N., & Bechinger, B. "Solid-state NMR studies of amphipathic helical DNA vectors and antibiotic peptides" European Biophysics Journal (2005) 34, 956 | | Aisenbrey, C., Goormaghtigh, E., Ruysschaert, J.-M., and Bechinger, B, "Translocation
of amino acids from the membrane interface to the interior: Theory and
Experimiment", European Biophysics Journal (2005) 34, 789 | | Aisenbrey, C. and Bechinger, B, "Investigations
of polypeptide topology and rotational diffusion in membranes by
solid-state NMR", European Biophysics Journal (2005) 34, 788 | | Bechinger, B. "Structure,
topology and dynamics of membrane-associated polypeptides by
solid-state NMR spectroscopy", FEBS J. Special issue: The protein
world, 272, 325 (2005) | | | |
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| | Book Chapters | |
Bechinger, B. Membrane-association and pore formation by alpha-helical peptides invited
contribution to ‘Proteins: Membrane Binding and Pore Formation,
Editors: G. Anderluth and Jeremy Lakey, Landes Biosciences (2010, in
press) | | |
Aisenbrey, C., Bertani, P., and Bechinger, B. Solid-state NMR of antimicrobial peptides in
Methods in Molecular Biology: Antimicrobial Peptides: Methods and
Protocols, Vol 618, pp. 209-233, Humana Press, editors: Andres C.
Rinaldi and Andrea Guiliani (2010) | | |
Bechinger,
B., Bertani, P., Werten, S., Mendonça de Moraes, C., Aisenbrey, C.,
Mason, A.J., Perrone, B., Prudhon, M., Sudheendra, U.S., and Vidovic, V. The
structural and topological analysis of membrane polypeptides by
oriented solid-state NMR spectroscopy: Sample preparation and theory.
Chapter 9 in "Membrane-active peptides: Methods and results on
structure and function" International University Line, La Jolla,
California, USA; editor Miguel Castanho, pp. 196-215 (2010, in press) | | Goldmann, W.H., Isenberg, G., Marsh, D., & Bechinger, B. Cytoskeletal proteins meet lipid bilayers in Planar Lipid Bilayers and Their Applications: Recent Progress Volume 8, Editor H.T. Tien (2007) | | Bechinger, B., and Henklein, P. Solid-state
NMR investigations of Vpu structural domains in oriented phospholipid
bilayers: Interactions and alignment, Chapter 13 in Viral membrane
proteins: Structure, function, drug design, editor: Wolfgang Fischer,
Volume 1 in Series Protein Reviews (editor M. Zouhair Atassa),
Publisher: Springer, pp. 177-186 (2005) | | | | |
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| | Patents | |
Kichler, A., Leborgne, C. and Bechinger, B. Vecteur peptidique pour le transfert d'acides nucléiques dans des cellules eucaryotes, Joint patent G143-B-18.120 FR and G143-B-18.120 PCT together with Généthon III, Evry, France (2001) | | Mason, J.A., Kichler, A., and Bechinger, B. US
Provisional Patent Application 60/720,878, The antibiotic and DNA
transfecting peptide LAH4 selectively associates with, and disorders,
anionic lipids in mixed membranes, 27. September 2005 | | Mason, A.J., Metz-Boutigue, M.H., Prévost, G. & Bechinger, B. US
Provisional Patent Application 60/815469, Designed histidine-rich
peptides with pH dependent antibiotic action against pathogenic
bacteria, 21. June 2006 | | Vidovic, V., Bechinger, B., and Werten S. US
Provisional Patent Application 61/065709, A versatile and highly
efficient method for the production of antimicrobial peptides in
Escherichia coli, 14. February 2008 | | Mason,J, Bechinger, B., Candolfi, E., Metz-Boutigue, M.H., Prevost, G. and Kichler, A. US
Provisional Patent Application 61/103321, Structural determinants of
antimicrobial and antiplasmodial activity and selectivity in histidine
rich amphipathic cationic peptides, 8. October 2008 | | |
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| | Others - General Public | |
Bechinger, B. Strukturuntersuchungen
an membrangebundenen Polypeptiden. Werkstätten der Zukunft 1997
(Editor: Pressestelle der Max-Planck-Gesellschaft 1997) | | |
Münster, C., Salditt, T., Bechinger, B., Siebrecht, R. and Leiner, V. Nonspecular neutron scattering from highly aligned lipid membranes The Institut Max von Laue – Paul Langevin, Annual Report, 17-18 (1999) | | |
Bechinger, B. Strukturuntersuchungen
an membrangebundenen Polypeptiden mittels Festkörper-NMR-Spektroskopie
Jahrbuch der Max-Planck-Gesellschaft 1999, 91-96 (1999) | | Bechinger, B. and others (written and edited by Frédéric Naudon, Alsace Media Science) "RMN: quand la matière résonne", dossier in ULP Sciences 26 (January 2007 | |
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