Dr. Jean Suffert Research Group

Our research group is located in the Faculty of Pharmacy in Strasbourg (France) and is a part of the Laboratory for Therapeutic Innovation (UMR CNRS/UDS 7200). Different groups compose this laboratory and each have their own scientific skills, such as organic synthesis, medicinal chemistry, molecular modeling, pharmacognosy and pharmacology, resulting in an academic plateform that can focus its research on a better understanding of cellular communication in living systems.

Our group is one of the teams constituting the International Center for Frontier Research in Chemistry (ICFRC).
In 2007, the French Government selected Strasbourg as the Center of Excellence in Chemistry for the country. ICFRC involves 80 teams in different institutes in Strasbourg comprising about 250 scientists and faculty members, 250 PhD students and 250 post-docs and technical staff.

Our team aim is to explore and provide new synthetic tools for the manufacturing of biomolecules. Our areas of interest include diastereoselectives reactions, multicomponante reactions, 1,3 dipolar species, heterocyclic chemistry, palladium chemistry, cascade/domino reactions, synthesis of complexes molecules, enediynes, anticancer agents.


unistra

cnrs

ICFRC
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Funded by :


idex

anr

pierre fabre

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AAREC
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News   (archives)

28.05.2013 : Dr. Jean Suffert is giving a lecture in Riga (Latvia)
Dr. Suffert is giving a lecture entitled "How to Make Complex Molecules from Simple Starting Material: the Palladium, a Powerful Tool" at the Bioheterocycles symposium 2013 : Link

07.05.2013 : Jean-Baptiste is flying to Cameroon!!!
As a part of collaboration with a lab in Cameroon, Jean-Baptiste is going there for 2 months in order to extract bioactive molecules from endemic plants.

April 2013 : Dr. Laurent Désaubry has given 2 lectures in the USA.
One in Harvard (MA), the othr one at the ACS Meeting in New-Orleans (LO).

02.04.2013 : Welcome to Sarah who is joining the group as a Master 2 trainee.

18.03.2013 : Congratulations to Dr. Mihaela Gulea who has been awarded an IdEx PhD grant.
More information about this position and the way candidates can apply to it will be soon posted on the dedicated "opportunities" webpage of this website - This position has been filled out

08.02.2013 : GECO symposium website is online
This symposium has been created to allow french researchers in organic chemistry to meet once a year in a friendly and informal ambiance in order to encourage the maximum interaction between the participants. LINK

30.01.2013 : Flavagline project highlighted by the CNRS !!!
CNRS has highlighted the flavagline-based project on his website. Well done Laurent !! LINK


Available Position(s)

  • A PhD fellowship in collaboration with ALSACHIM (CIFRE) is currently available in our group. Please contact Dr. Jean Suffert for more information. PDF (in french) of the offer : Link

Selected Recent Publications

  • Chem Biol., 2013, 20, 316-331

Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential.

  • Angewandte Chemie int. Ed. 2012, 51, 4379

An Expeditious and Atom-Economical Synthesis of a New Generation of Substituted [4.6.4.6]Fenestradienes.

  • J. Org. Chem., 2012, 77, 2246–2253

Stereoselective Multicomponent Assembly of Enantiopure Oxazolopiperidines and -azepines.

  • J. Med. Chem., 2012, 55, 10064–10073

Flavaglines as Potent Anticancer and Cytoprotective Agents.

  • Angewandte Chemie int. Ed. 2011, 50, 3285
Step-Economical Synthesis of Taxol-like Tricycles through a Palladium-Catalyzed Domino Reaction.